Biochem/physiol Actions

Cell permeable: no

Reversible: no

Primary TargetColorimetric substrate for the detection of granzyme B and caspase-8 activity

Product does not compete with ATP.

General description

Colorimetric substrate for the detection of granzyme B and caspase-8 activity. Cleavage of pNA is monitored colorimetrically at ~405 nm.

Colorimetric substrate for detection of granzyme B. Cleavage is monitored colorimetrically at ~405 nm.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.

Packaging

5 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sequence

Ac-Ile-Glu-Thr-Asp-pNA

Warning

Toxicity: Standard Handling (A)